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Design and Analysis of Vaccine Studies Cover Image E-book E-book

Design and Analysis of Vaccine Studies [electronic resource] / by M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner.

Record details

  • ISBN: 9780387686363
  • Physical Description: online resource.
  • Publisher: New York, NY : Springer New York, 2010.
Subject: Statistics.
Emerging infectious diseases.
Statistics.
Statistics for Life Sciences, Medicine, Health Sciences.
Infectious Diseases.

Electronic resources


Overview of vaccine effects and study designs
Immunology and early phase trials
Binomial and stochastic transmission models
R[o] and deterministic models
Evaluating protective effects of vaccination
Models of action and time-varying VE[s]
Further evaluation of protective effects
Vaccine effects on post-infection outcomes
Household-based studies
Analysis of households in communities
Analysis of independent households
Assessing indirect, total, and overall effects
Randomization and baseline transmission
Surrogates of protection.

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