E-book
Phosphoinositide 3-kinase in Health and Disease [electronic resource] : Volume 1 / edited by Christian Rommel, Bart Vanhaesebroeck, Peter K. Vogt.
Record details
- ISBN: 9783642136634
- Physical Description: X, 310 p. digital.
- Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2011.
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| Subject: | Medicine. Oncology. Human physiology. Biomedicine. Cancer Research. Human Physiology. Molecular Medicine. |
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Other Formats and Editions
Electronic resources
| PI3K | ||
| From the Bench to the Clinic and Back | ||
| PI3K Book Introduction | ||
| PDK1: The major transducer of PI 3-Kinase actions | ||
| Protein Kinase B (PKB/Akt), a key mediator of the PI3K signaling pathway | ||
| Regulatory subunits of class IA PI3K | ||
| The Regulation of Class IA PI 3-kinases by Inter-Subunit Interactions | ||
| Phosphoinositide signalling pathways in metabolic regulation | ||
| Role of RAS in the regulation of PI 3-kinase | ||
| More than just kinases: The scaffolding function of PI3K | ||
| PI3K signalling in neutrophils | ||
| PI 3-kinase p110beta regulation of platelet integrin alphaIIbbeta3 | ||
| PI3Ks in lymphocyte signalling and development | ||
| PI3 kinase regulation of skeletal muscle hypertrophy and atrophy | ||
| Taking PI3Kdelta and PI3Kgamma one step ahead | ||
| Dual active PI3Kdelta/gamma inhibitors for the treatment of immune-mediated inflammatory diseases | ||
| Oncogenic Mutations of PIK3CA in Human Cancers | ||
| Structural Effects of Oncogenic PI3Kalpha Mutations | ||
| Comparing the roles of the p110alpha and p110beta isoforms of PI3K in signaling and cancer | ||
| Phosphatidylinositol 3-kinase (PI3K): The oncoprotein | ||
| AKT Signaling in Physiology and Disease | ||
| Faithfull modeling of PTEN loss driven diseases in the mouse | ||
| PI3K as a target for therapy in haematological malignancies | ||
| Clinical development of Phosphatidylinositol-3 kinase pathway inhibitors | ||
| New inhibitors of the PI3K-Akt-mTOR pathway: Insights into mTOR signaling from a new generation of Tor kinase domain inhibitors (TORKinibs) | ||
| Small molecule inhibitors of the PI3-kinase family | ||
| Targeting the RTK-PI3K-mTOR axis in malignant glioma: overcoming resistance | ||
| Subject index. |
